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METSALBEN-10%; 20%

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1. GENERAL INFORMATION
1.1 Metsalben 10% & 20%" is ready for use granular anthelmintic drug containing 10% or 20% albendazole as active ingredient and fillers (lactose, feeding chalk, precipitated chalk, starch and other inert compounds).

1.2 The drug by its appearance is granules with light gray color, faint specific odor, well disintegrated in damp fodder.

1.3 The drug is available in two-layer hermetically sealed plastic bags by 0.1 to 0.5 kg and in polymer jars by 0.5 to 10.0 kg.

1.4 The drug should be stored in the original container in dry, dark place, out of reach of children at the temperature range +5°C to +30°C. Shelf-life of the drug is 3 years from date of manufacture under specified storage conditions.

2. PHARMACOLOGICAL PROPERTIES
2.1 Albendazole has a wide range of action it causes destruction of eggs and mature stages of trematodes, mature and immature stages of nematodes and cestodes. It breaks energy metabolism, inhibits fumarate reductase activity that leads to disruption of adenosinetrphosphoric acid synthesis in helminthes.

 

3. DRUG USAGE PROCEDURE      
3.1 Mecalben is administered in large and small cattle, pigs and dogs once by group method in mixture with feed without prior starvation diet in the following doses (mg per 1 kg animal weight):
Animal species and names of helminthoses  10% Granulate  20% Granulate ADB
In cattle:
- dictyocaulosis, strongylatosis of gastrointestinal tract, strongyloidosis;
- fascioliasis, paramphistomatosis, moniaziasis, trichocephaliasis
 75 100  37,5 50  7,5 10
In ruminants:
- dictyocaulosis, strongylatosis of gastrointestinal tract, strongyloidosis;
- fascioliasis, moniaziasis
 50 75  25 37,5  5,0 7,5
In pigs:
ascaridosis, trichocephaliasis, esophagostomiasis, strongyloidosis
75 37,5 7,5
In dogs:
- toxascaridosis, toxocariasis, uncinariosis, taeniosis
200
100
20
If required the drug may be administered repeatedly.

3.2 No side effects have been observed by using the drug in recommended doses.

3.3 Slaughter for meat of cattle and pigs shall be allowed not earlier than 14 days, sheep and goats - 10 days, use of milk obtained from cows for food purposes - after 3 days and milk obtained from sheep and goats - 4 days after the last drug administration. Meat of compulsory slaughtered animals and milk obtained prior specified deadline may be used for feed purposes.

 

4.  INDIVIDUAL PREVENTION MEASURES
4.1 A person working with this drug shall follow general personal hygiene regulations and safety precautions, envisaged for operations with veterinary drugs.

4.2 At the end of operations you should wash your hands with warm water and soap.

 

5. CLAIMS PROCEDURE
5.1 In case of inconsistency of the drug with requirements of this Instruction, its use should be discontinued and reported to the Uzbek state scientific and veterinary drugs control laboratory at: 700178, Tashkent, No.1a, A.Yunusov Street. Tel. / Fax: 228-76-14, 229-30 - 47. E-mail: uzgnkl@rambler.ru. Simultaneously unpacked drug package should be sent to the laboratory address with the drug in quantity previously agreed with laboratory including detailed description of the nature of complications.