1. GENERAL INFORMATION
1.1 Metsalben-360 tablets.
1.2 The drug contains albendazole (0,36g per tablet) as an active ingredient as well as other auxiliary compounds.
1.3 The drug by its appearance are pills with correctly rounded shape, gray or gray with cream shade color.
1.4 Metsalben-360 tablets are prepackaged by 25-200 or 10-20 pcs in individual strip package (blister).
2. PHARMACOLOGICAL PROPERTIES
2.1 Albendazole is a broad-spectrum anthelmintic, active against mature and immature nematodes, cestodes as well as against mature trematodes. The drug has a wide range of actions, causing death to adult and larval forms of helminthes.
2.2 Mechanism of the albendazole action as a part of the drug is disruption of carbohydrate metabolism in helminthes, which leads to its destruction and withdrawal from the animal body. When administered orally albendazole is quickly absorbed by gastrointestinal tract and penetrates into organs and tissues; it is eliminated from the body mainly with urine and faeces. Due to its egg-killing action it reduces pasture infestation by helminthes.
2.3 The drug is moderately hazardous by degree of impact on the body. It is well tolerated by animals in recommended doses.
3. DRUG USAGE PROCEDURE
3.1 Metsalben-360 is administered for deworming of cattle, sheep, goats, pigs, horses in the following diseases:
- gastrointestinal nematodosis (haemonchosis, bunostomatosis, esophagostomiasis, nematodirosis, ostertagiosis, chabertiosis, cooperiosis, strongyloidosis, trichostrongylosis, giostrongilosis, parascaridosis, ascaridosis);
- pulmonary nematodosis (dictyocaulosis, protostrongylosis, mulleriosis, neostrongylosis, cystocaulosis, metastrongylosis);
- cestodiasis (monieziasis, avitellinosis, thysanieziosis);
- trematod infection (fascioliasis, dicroceliosis, paramphistomatosis).
3.2 The tablets are administered orally compulsory at the tongue root, once, in the following doses.
In cattle: 1 tablet per 50 kg; for treatment of fascioliasis, dicroceliosis paramphistomatosis, ostertagiosis – 1 tablet per 35 kg animal weight.
In sheep and goats: 1 tablet per 70 kg; for treatment of fascioliasis, dicroceliosis, protostrongylidoses – 1 tablet per 35 kg animal weight.
In pigs: 1 tablet per 35 kg.
In horses: 1 tablet per 50 kg. Special diet and use of laxatives before deworming is not required.
3.3 Prior to mass deworming every batch of the drug shall be pre-tested in a small group of animals (5-10 animals). In absence of complications within 3 days you can start treatment in all livestock.
3.4 Side effects. No side effects have been observed by using Metsalben-360 in recommended doses.
3.5 Contraindications. The drug shall not be used in acute fascioliasis, during breeding period, in sick animals with infectious diseases and emaciated animals, as well as in sheep, goats and pigs in the first half, and in cows and mares - in the first trimester of pregnancy.
3.6 Slaughter for meat of cattle, horses and pigs shall be allowed not earlier than 14 days and 10 days respectively, use of milk obtained for food purposes - after 3 and 4 days respectively after the last drug administration. Meat of compulsory slaughtered animals and milk obtained prior specified deadline may be used as feed for fur-bearing animal and in production of meat and bone tankage.
4. INDIVIDUAL PREVENTION MEASURES
4.1 All operations with the drug shall be made in protective clothing (dressing, headwear, rubber goggles). In case of accidental contact of the drug with skin or mucous membranes you must rinse with large amount of water.
4.2 Do not drink, smoke and eat during operations.
4.3 At the end of operations you should wash your hands with warm water and soap; Wash and dry your gloves.
4.4 Do not use containers under the drug for other purposes.
5. CLAIMS PROCEDURE
5.1 In case of inconsistency of the drug with requirements of this Instruction, its use should be discontinued and reported to the Uzbek state scientific and veterinary drugs control laboratory at: 700178, Tashkent, No.1a, A.Yunusov Street. Tel. / Fax: 228-76-14, 229-30 - 47. E-mail: firstname.lastname@example.org. Simultaneously unpacked drug package should be sent to the laboratory address with the drug in quantity previously agreed with laboratory including detailed description of the nature of complications.