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POLIMER YOD-10%

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1. GENERAL INFORMATION
1.1 Polymer-iodine 10% solution

1.2 The drug is a viscous dark brown liquid, well soluble in water. Each gram of Polymer-iodine 10% solution contains 100 mg of active iodine in the form iodine-polymeric complex.

1.3 The drug is pre-packaged in glass vials by 10 - 250 ml and in polymer bottle (canister) by 0.1 - 0.5 l.

1.4 The drug should be stored with caution (see list B) in dark place protected from direct sunlight within the temperature range 0°C to +25°C. Shelf life is 24 months from date of manufacture.

2. PHARMACOLOGICAL PROPERTIES
2.1 This drug due to availability of active iodine has a broad spectrum of activity against nonspore-forming microbes (except for mycobacteria), viruses and fungi. The drug belongs to the group of moderately toxic compounds. Solutions do not have irritating effects and do not cause corrosion of metals.

2.2 Polymer-iodine 10% solution in accordance GOST 12.1.007 - 76 based on parameters of acute toxicity when injected into stomach it belongs to Category 3 moderately hazardous substances and when contacting with skin - to Category 4 Low Hazard substance; it does have locally - irritating and sensitizing effects on skin and causes mild irritation of mucous membranes. Mist of the drug have moderate hazard in saturating concentrations.

 

3. DRUG USAGE PROCEDURE
3.1 Wet disinfection. For preventive and compulsory (regular and final) disinfection during infections related to sensitive group (I group) and stable groups(II group) against main disinfectants, when disinfection quality is controlled by extraction of Escherichia coli and Staphylococcus, 1% drug solution is administered based on 0.2 - 0.3 l / m ² of treated surface. Exposure duration during preventive and final disinfection is 3 hours and for regular disinfection is 1 hour. Aerosol disinfection. For preventive and compulsory (regular and final) disinfection during infections related to resistant groups I and II, 1.5% drug solution based on 30 ml / m³ is applied. Exposure duration during preventive and final disinfection is 3 hours and during regular disinfections - 1 hour.

3.2 For treatment of respiratory diseases - laryngotracheitis, infectious bronchitis, aspergillosis, infectious rhinotracheitis, bronchitis and bronchopneumonia in calves, young pigs and lambs as well as during mixed infections, 0.5% solution based on 5 - 10 ml / m³. Total exposure duration in animals is 60 minutes per day. Treatment is performed 3 - 5 times in every second day.

3.3 Treatment of wound surfaces. 5% drug solution is used for disinfection of skin and wound treatment in animals (castration, operation, fresh and complicated infections), treatment of umbilical cord, external genitals.

3.4 Treatment of necrobacillosis and foot rot in cattle, sheep and goats. Affected area shall be previously cleaned from mechanical impurities. Undiluted Polymer-iodine 10% is applied by richly moistened gauze tampon on the cleaned area. Treatment shall be performed tree times with one day interval.

3.5 Side effects and complications. No side effects and complications as a result of Polymer-iodine 10% use are revealed under recommended doses and treatment conditions.

3.6 Contraindications. Contraindication for use of drug is increased individual sensitivity to iodine in animal. In such case treatment should be discontinued.

 

4. PREPARATION OF THE DRUG WORKING SOLUTION
4.1 Working solution is prepared in clean container made ​​of glass or polymer material by dilution of the drug with distilled or boiled tap water based on calculation in the table. Working solutions are prepared on the day of its application. Preparation of the Polymer-iodine 10% working solutions.

Concentration of the working solution by active iodine  Quantity of «Polymer-iodine 10%» (10% of active iodine) and water for preparation
of the working solution with relevant concentration 
0,5 liters 1,0 liter 10 liters 50 liters
Drug, g Water,ml Drug, g Water,ml Drug, g Water,ml Drug, g Water,ml
0,2% 10,0 490,0 20,0 980,0 0,2 9,80 1,0 49,0
0,5% 25,0 475,0 50,0 950,0 0,5 9,50 2,5 47,5
1,0% 50,0 450,0 100,0 900,0 1,0 9,00 5,0 45,0
1,5% 75,0 425,0 150,0 850,0 1,5 8,50 7,5 42,5
5,0% 250,0 250,0 500,0 500,0 5,0 5,0 25,5 25,0

 

5. PREVENTION MEASURES AND FIRST AID  
5.1 All works should be carried out by using protective clothing (coat, hat, rubber gloves). Do not drink, smoke and eat during operations.

5.2 After completion of works you should wash your hands, face and exposed parts of the body with warm water and soap; wash and dry used gloves.

5.3 Failure to observe precaution measures there may be manifestations of irritation to respiratory organs, mucous membranes of eyes.

5.4 After contact of the drug with skin you should wash it off with water. In case of accidental contact with eyes, immediately rinse it under running water for 10 - 15 min., and then by 2% solution of baking soda. If hyperemia occurs you should drop 30% solution of sulfacyl sodium. If necessary - consult an eye specialist.
If you accidentally swallow it is required to take abundant food (warm milk with Borjomi or baking soda). If necessary, consult a doctor.
If irritation of upper respiratory tract is observed the victim must be released from work and get out into fresh air or into well ventilated room, rinse nasopharynx and give him warm drinks. If necessary, consult a doctor.

5.5 Do not use containers under the drug for food purposes.

 

6. CLAIMS PROCEDURE
6.1 In case of complications after drug administration its use should be discontinued and reported to the Uzbek State Scientific and Veterinary Drugs Control Laboratory (700178, Tashkent, Karakamysh 2/4, No.1a, A.Yunusov str.) and to the drug manufacturer. Simultaneously samples of drug’s lot should be sent to the Uzbek State Scientific and Veterinary Drugs Control Laboratory samples expelled Series drug that caused complications in animals, with detailed description of complications.