1. GENERAL INFORMATION
1.1 Polysulfon (Polysulfonum) is an integrated acaricide preparation which aqueous solution contains sulfur alkaline dissolution products, dimethyl sulphoxide and stabilizer. Total sulfur content in the drug is 5 %.
1.2 The drug is a clear solution with yellow to brown color and specific odor. Presence of slight sediment in the drug is acceptable
1.3 Polysulphone is pre-packed into glass or polymer consumer packaging 50.0 to 1000.0 cm³.
1.4 The drug is stored with caution (See List ‘B’) and protected from light at temperatures +4°C to +20°C. Expiry date is 1 year from the date of manufacture.
2. PHARMACOLOGICAL PROPERTIES
2.1 When interacting with alkalies sulfur is converted into active compound. After applying the drug on skin molecular sulfur, hydrogen sulfide and sulfur dioxide start to generate, which act with acaricide and aseptic effect and stimulate skin receptors.
2.2 Sulfur antiscabietic effect is due to its acaricide properties and in particular due to presence of its irritant effects. Due to irritation of skin receptors epidermis peeling is occurred that significantly improves metabolism and mites are being removed.
2.3 The most effective drug effect is observed at optimal moisture content and at temperature +30 ° C. At high humidity air a part of sulfur dioxide is converted into sulfuric acid, which highly irritates the skin of animals, poorly penetrates through mite’s chitinous cover whereby acaricide effect of the drug is decreased.
2.4 Polysulphone has an acaricid effect against scabies mite’s species like Sarcoptes, Psoroptes, and Otodectes.
3. DRUG USAGE PROCEDURE
3.1 The drug is used in cattle and small ruminants, horses, pigs and pets and fur animals.
3.2 The drug is applied to the skin areas affected by scabies mites after preliminary treatment (washing with warm water and soap and removing crusts). Treatment shall be repeated twice with 8-10 days interval.
3.3 During treatment of scabies in small animals after pre-treatment and removal of crusts an affected ear should be thoroughly lubricated and 5-7 drops of the drug shall be instilled and ear massage shall be performed from the ear root to the ear tip. Repeated treatment shall be carried out after 7-10 days.
3.4 There are no contraindications for the drug use.
3.5 Meat and milk of the treated animals may be used without limitations.
4. INDIVIDUAL PREVENTION MEASURES
4.1 In case of skin or eye mucosa exposure you should wash out with plenty of water.
4.2 After handling the product you should carefully wash hands and face with warm water.
5. CLAIMS PROCEDURE
5.1 In case of inconsistency of the drug with requirements of this Instruction, its use should be discontinued and reported to the Uzbek State Scientific and Veterinary Drugs Control Laboratory at: 700178, Tashkent, No.1a, A.Yunusov Street. Tel. / Fax: 228-76-14, 229-30 - 47. E-mail: email@example.com. Simultaneously unpacked drug package should be sent to the laboratory address with the drug in quantity previously agreed with laboratory including detailed description of the nature of complaints regarding its inconsistency with this Instruction.