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OKSITOTSIN SOLUTION

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1. GENERAL INFORMATION        
1.1 Oksitotsin Solution.        

1.2 Oxytocin (synthetic analogue of polypeptide hormone of the posterior pituitary) is an active component of the drug. Oksitotsin solution for veterinary is available in two versions containing 5 units or 10 units of oxytocin in 1 ml.        

1.3 The drug is sterile clear, colorless liquid with specific odor, without visible mechanical impurities.         

1.4 The drug is pre-packed in glass vials by 10; 20; 50 and 100 ml. The drug should be stored under list B in dry place, protected from sunlight within the temperature range 2°C to +10ºC. Shelf life is 18 months from the date of its production under specified storage conditions.

2. PHARMACOLOGICAL PROPERTIES        
2.1 Oksitotsin solution improves tone and intensifies contraction of the uterus smooth muscle, causes contraction of myoepithelial cells surrounding alveoli of the lacteal glands, stimulating lactation in lactating animals.        

2.2 The drug has weak vasopression alike, antidiuretic properties.

 

3. DRUG USAGE PROCEDURE
3.1 Oksitotsin solution is used in female farm and domestic animals for treatment of weak expulsive pains during delivery, retention of placenta, uterine bleeding, atony, hypotonia and inflammation of uterus, mastitis and reflectory agalactia.

3.2 The drug is administered subcutaneously, intramuscularly, intravenously (slowly), as required - in combination with Novocaine epidurally in the following doses:

Species  Injection types and doses (units)
Subcutaneously or
intramuscularly 
Intravenously  Epidurally 
Mares and cows 30-60 20-40 15-30
Breeding sow under 200 kg 30 20 10-15
Goats and sheep  10-15 8-10 -
Dogs  5-10 2-7 -
Cats 3 2 2

3.3 Side effects: vomiting, tachycardia, hypotension, premature detachment of placenta. Uncoordinated or overly intensive labors may occur after drug overdose.

3.4 The drug is contraindicated in pregnant animals, labor induction in cases of imbalance between fetus and pelvis sizes, fetal malformations as well as during malposition and attitude.

3.5 Animal products during and after treatment shall be used without limitations.

 

4. CLAIMS PROCEDURE
4.1 In case of inconsistency of the drug with requirements of this Instruction, its use should be discontinued and reported to the Uzbek State Scientific and Veterinary Drugs Control Laboratory at: 700178, Tashkent, No.1a, A.Yunusov Street. Tel. / Fax: 228-76-14, 229-30 - 47. E-mail: uzgnkl@rambler.ru. Simultaneously unpacked drug package should be sent to the laboratory address with the drug in quantity previously agreed with laboratory including detailed description of the nature of complaints regarding its inconsistency with this Instruction.